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李阳

副标题:

 

姓名

李阳

性别

职务

-

职称

副研究员

地址

福建省厦门市集美区兑山西珩路258号

邮箱

li.yangfjirsm.ac.cn

邮编

361021

 

    简介:

 
    李阳,博士,副研究员。

 
    2018.09至今 网上十大正规赌网址大全,副研究员

 
    研究领域:

 
    纳米药物与纳米生物材料的设计合成、组装构筑及其构效关系、协同功能、临床应用中生物机制的研究 

    主要科研成果:

 
    硕博与博后期间先后师从张其清、戴李宗、侯振清教授,主要研究领域涉及生物材料与纳米药物自组装体的结构设计与构筑、性能调控以及其恶性肿瘤高效低毒诊疗应用研究等,先后主持中国博士后科学基金特别资助项目(15万)、面上项目(5万),另以合作单位负责人主持国家自然科学基金面上项目(12.5万)。工作期间主持福建省孟超肝胆技术联合创新重点实验室开放项目(3万)。近4年来在Journal of Controlled Release、Molecular Pharmaceutics、ACS Applied Materials & Interfaces、Journal of Materials Chemistry B、International Journal of Pharmaceutics等国际知名期刊上发表20余篇SCI论文,其中第一作者12篇(IF累计为73.2,2篇2区入选ESI高被引论文),通讯作者4篇,共一作者5篇。 

    近期论文论著:

 
    1) Li Y., Liu G., Ma J., Lin J., Lin H., Su G., Chen D., Ye S., Chen X., Zhu X., Hou Z. Chemotherapeutic drug-photothermal agent co-self-assembling nanoparticles for near-infrared fluorescence and photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy. J. Controlled Release, 2017, 258: 95-107.(1区. IF: 7.9. Referenced: 37)

 
    2) Li Y., Lin J., Ma J., Song L., Lin H., Tang B., Chen D., Su G., Ye S., Zhu X., Luo F., Hou Z. Methotrexate-camptothecin prodrug nanoassemblies as a versatile nanoplatform for biomodal imaging-guided self-active targeted and synergistic chemotherapy. ACS Appl. Mater. Interfaces, 2017. 9: 34650-34665.(1区. IF: 8.1. Referenced: 12)

 
    3) Li Y., Song L., Lin J., Ma J., Pan Z., Zhang Y., Su G., Ye S., Luo F., Zhu X., Hou Z. Programmed nanococktail based on pH-responsive function switch for self-synergistic tumor-targeting therapy. ACS Appl. Mater. Interfaces, 2017. 9: 39127-39142.(1区. IF: 8.1. Referenced: 6)

 
    4) Li Y., Lin J., Yang X., Li Y., Wu S., Huang Y., Ye S., Xie L., Dai L., Hou Z. Self-assembled nanoparticles based on amphiphilic anticancer drug-phospholipid complex for targeted drug delivery and intracellular dual-controlled release. ACS Appl. Mater. Interfaces, 2015, 7: 17573-17581.(1区. IF: 8.1. Referenced: 37)

 
    5) Li Y., Lin J., Li Y., Huang Y., Yang X., Wu H., Xie L., Dai L., Hou Z. Self-targeted, shape-assisted, and controlled-release self-delivery nanodrug for synergistic targeting/anticancer effect of cytoplasm and nucleus of cancer cells. ACS Appl. Mater. Interfaces, 2015. 7: 25553-25559.(1区. IF: 8.1. Referenced: 34)

 
    6) Li Y., Zhang H., Chen Y., Ma J., Lin J., Zhang Y., Fan Z., Su G., Xie L., Zhu X., Hou Z. Integration of phospholipid-hyaluronic acid-methotrexate nanocarrier assembly and amphiphilic drug-drug conjugate for synergistic targeted delivery and combinational tumor therapy. Biomater. Sci., 2018. 6: 1818-1833.(2区. IF: 5.8. Referenced: 0)

 
    7) Li Y., Lin J., Wu H., Jia M., Yuan C., Chang Y., Hou Z., Dai L. Novel methotrexate prodrug-targeted drug delivery system based on PEG-lipid-PLA hybrid nanoparticles for enhanced anticancer efficacy and reduced toxicity of mitomycin C. J. Mater. Chem. B, 2014, 2: 6534-6548.(1区. IF: 4.8. Referenced: 19)

 
    8) Li Y., Lin J., Wu H., Chang Y., Yuan C., Liu C., Wang S., Hou Z., Dai L. Orthogonally functionalized nanoscale micelles for active targeted codelivery of methotrexate and mitomycin C with synergistic anticancer effect. Mol. Pharmaceutics, 2015, 12: 769-782.(2区. IF: 4.6. Referenced: 45) 


    9) Li Y., Wu H., Yang X., Jia M., Li Y., Huang Y., Lin J., Wu S., Hou Z. Mitomycin C-soybean phosphatidylcholine complex-loaded self-assembled PEG-Lipid-PLA hybrid nanoparticles for targeted drug delivery and dual-controlled drug release. Mol. Pharmaceutics, 2014, 11: 2915-2927.(2区. IF: 4.6. Referenced: 35)

 
    10) Li Y., Wu H., Jia M., Cui F., Lin J., Yang X., Wang Y., Dai L., Hou Z. Therapeutic effect of folate-targeted and PEGylated phytosomes loaded with a mitomycin C-soybean phosphatidyhlcholine complex. Mol. Pharmaceutics, 2014, 11: 3017-3026.(2区. IF: 4.6. Referenced: 29)

 
    11) Hou Z.#,(导师为通讯作者)Li Y.#,(第一作者)Huang Y., Zhou C., Lin J., Wang Y., Cui F., Zhou S., Jia M., Ye S., Zhang Q. Phytosomes loaded with mitomycin C-soybean phosphatidylcholine complex developed for drug delivery. Mol. Pharmaceutics, 2013, 10: 90-101.(2区. IF: 4.6. Referenced: 68)

 
    12) Li Y., Lin J., Liu G., Ma J., Xie L., Guo F., Zhu X., Hou Z. Dual-acting, function-responsive, and high drug payload nanospheres for combining simplicity and efficacy in both self-targeted multi-drug co-delivery and synergistic anticancer effect. Int. J. Pharm., 2016, 512: 194-203. (2区. IF: 3.9. Referenced: 4) 

 

 



 

 

 

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